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      1. 當前位置:產品與服務 >替米沙坦
        替米沙坦

        基本信息
        化學名稱:4′-[4-甲基-6-(1-甲基-1H-苯并咪唑-2-基)-2-丙基-1H-苯并咪唑基甲基]聯苯基-2-羧酸
        分子式:C33H30N4O2
        分子量: 514.62
        CAS NO:144701-48-4
        質量標準:USP/ EP/ 國家標準, 可提供DMF/ CEP/ GMP。


         Specification

             According to European Pharmacopoeia 7.8

        Items

        Specification

        Results

        Appearance

        White or slightly yellowish crystalline powder

        White crystalline powder

        Solubility

        Should meet the requirement

        Conforms

        IR Identification

        Should correspond to the RS Infrared Absorption

        Correspond to the reference substance

        Appearance of solution

        Should meet the requirement

        Conforms

        Related substance

        Impurity A

        ≤0.15%

        0.05%

        Impurity B

        ≤0.15%

        0.02%

        Impurity C

        ≤0.2%

        0.03%

        Impurity D

        ≤0.2%

        0.05%

        Unspecified Ims.

        ≤0.1%

        0.06%

        Total

        ≤1.0%

        0.30%

        Residual solvents

        Methanol

        ≤0.3%

        Not detected

        Ethanol

        ≤0.5%

        0.031%

        Methylene dichloride

        ≤0.06%

        Not detected

        n-hexane

        ≤0.029%

        Not detected

        Acetic acid ethyl ester

        ≤0.5%

        Not detected

        Toluene

        ≤0.089%

        0.025%

        Acetic acid

        ≤0.5%

        0.036%

        Loss on drying

        ≤0.5%

        0.20%

        Sulphated ash

        ≤0.1%

        Conforms

        Melting point

            261 ºC -263 ºC

             261.1 ºC -262.2 ºC

        Particle size

            90% Less than 200um

             Conforms

        Assay

            99.0%~101.0%

             99.9%

        Conclusion

           It conforms to European Pharmacopoeia 7.0

        作用與用途:用于原發性高血壓的治療。

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